Alcoholism medication

Medication May Stop Drug and Alcohol Addiction, UT News, The University of Texas at Austin

AUSTIN, Texas —  Researchers at The University of Texas at Austin have successfully stopped cocaine and alcohol addiction in experiments using a drug already approved by the U.S. Food and Drug Administration (FDA) to treat high blood pressure. If the treatment is proven effective in humans, it would be the first of its kind — one that could help prevent relapses by erasing the unconscious memories that underlie addiction.The research is published this week in the journal Molecular Psychiatry.Scientists once believed that drug addiction was simply a physical craving: Drug addicts who became sober and then later relapsed merely lacked willpower. But that view has gradually shifted since the...

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Alcohol detoxification - Wikipedia, the free encyclopedia

Alcohol detoxificationAlcohol detoxification, or detox, for individuals with alcohol dependence, is the abrupt cessation of alcohol intake, a process often coupled with substitution of cross-tolerant drugs that have effects similar to the effects of alcohol in order to prevent alcohol withdrawal. Introduction [ edit ] As such, the term "detoxification" may be somewhat of a misnomer since the process need not refer exclusively to the removal of toxic substances from the body. Detoxification may or may not be indicated depending upon an individual's age, medical status, and history of alcohol intake. For example, a young man who binge drinks and seeks treatment one week after his last use of...

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Naltrexone in the Treatment of Alcohol Dependence NEJM

Naltrexone in the Treatment of Alcohol DependenceJohn H. Krystal, M.D., Joyce A. Cramer, B.S., William F. Krol, Ph.D., Gail F. Kirk, M.S., and Robert A. Rosenheck, M.D., for the Veterans Affairs Naltrexone Cooperative Study 425 GroupResultsThe study was conducted from April 1997 to October 2000. We screened 3372 alcohol-dependent veterans to assign 627 patients to three groups of 209 patients each (with 30 to 50 patients per site). Base-line characteristics of the patients are shown in Table 1 Table 1 Base-Line Characteristics of the 627 Patients., and adverse events during treatment in Table 2 Table 2 Adverse Events Reported More Commonly in the Naltrexone Group Than in the Placebo Group...

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A common drug for ulcers could prevent alcohol abuse, Ars Technica

There are almost no medicines available to treat alcoholism, but that might be about to change. A new study shows that a substance commonly used to treat stomach ailments may also hold the key to reducing the craving for alcohol.Many of the scientists involved in the study, published recently in Translational Psychiatry, have been studying the molecular mechanisms of alcoholism in the body for years. One focus of their work is the way our bodies produce glucocorticoids, which are steroid hormones that help our immune systems function smoothly and reduce inflammation. People who drink compulsively often suffer from disruptions in the regulation of glucocorticoids in their bodies.Previous...

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Surgeon General calls for action to fight drug, alcohol abuse Reuters

WASHINGTON The U.S. Surgeon General issued a call to action on Thursday to end what he called a public health crisis of drug and alcohol addiction that is underappreciated and undertreated.Dr. Vivek Murthy issued the first-ever Surgeon General's report on addiction and said he hopes it will galvanize work on the issue the way a similar report more than 50 years ago sparked decades of effort to combat smoking.U.S. deaths from drug overdoses hit a record in 2014, increasing 6.5 percent to 47,055, propelled by prescription painkiller and heroin abuse, according to the Centers for Disease Control and Prevention."The most important thing is, we have to change attitudes towards addiction and get...

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Could Asthma Medication or Special K Cure Alcoholism?

At the core of my being, I am incredibly lazy. When I first heard the word “work” tossed around in meetings, I cringed. I mean I wanted to get sober but “work”? Ugh. That sounded hard. Couldn’t I just show up once or twice and poof! I’m cured and no longer drink and use drugs like a total pig?Alas, that wasn’t the case. And some eight years later, I’m still doing the work. Yet the lazy bunny inside of me still thrills at the idea of a magical pill that can cure alcoholism. Recently, two separate studies revealed the possibility of medications holding the key to curing alcoholism, and I gotta say: the thought is still pretty darn appealing.Breathe EasyThe idea that a cure for something as...

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Cannabis as a substitute for alcohol and other drugs, Harm Reduction Journal, Full Text

AbstractBackgroundIt has been observed that those who use large amounts of cannabis frequently use other drugs as well, especially alcohol. This can create a potential synergistic effect, resulting in increased harms [ 1 – 4 ]. Economic research has looked at the substitution and complimentarity of particular substances by modelling the effects of price fluctuation on use, although the limits of such research have been noted [ 5 ]. When considering youth, Pacula has found cannabis and alcohol to be compliments. As beer prices rose, cannabis use declined [ 6 ]. This could potentially be because the introduction of alcohol into an adolescent environment increases the likelihood of other...

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Medication to Help Curb Alcoholism Expected Soon - Alcoholism Rehab

Medication to Help Curb Alcoholism Expected SoonIndividuals dependent on alcohol to function in life often find they cannot get out from underneath this addiction. Now, according to a recent news report, a new medication could offer the answer.This medication is designed to reduce alcohol dependency and is expected to be on the market in a little more than a year. The new medication is expected to lessen the urge to drink excessive amounts of alcohol.Known as Nalmefene, the new drug has been developed by Biotie Therapies in Turku, which is located in south western Finland. The license for the drug was purchased by the Danish Lundbeck company in 2006. Results from clinical trials are...

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Novel Medication Targets for the Treatment of Alcoholism: Preclinical Studies, BenthamScience

Recent Patents on CNS Drug Discovery (Discontinued) Istituto di Chimica Biomolecolare (I.C.B.)Consiglio Nazionale delle Ricerche (C.N.R.)Novel Medication Targets for the Treatment of Alcoholism: Preclinical StudiesKeywords: Alcohol intake, ALDH2 inhibitor, carisbamate, inbred alcohol-preferring rats, inbred fawn-hooded rats, JNJ- 5234801, JNJ-39220675, RWJ-333369, sazetidine-A, CVT-10216, GS-455534, Novel Medication Targets, Treatment of AlcoholismTitle:Novel Medication Targets for the Treatment of Alcoholism: Preclinical StudiesAuthor(s):Amir H. Rezvani, Andrew J. Lawrence, Maria P. Arolfo, Edward D. Levin and David H. OverstreetAffiliation:Dept. of Psychiatry and Behavioral Sciences, Box...

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Medication for Alcoholism

Medication for Alcoholism: What helps...

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