Medicine alcoholism

Enzyme malfunction may be why binge drinking can lead to alcoholism, News Center, Stanford Medicine

A new study in mice shows that restoring the synthesis of a key brain chemical tied to inhibiting addictive behavior may help prevent alcohol cravings following binge drinking.A malfunctioning enzyme may be a reason that binge drinking increases the odds of alcoholism, according to a study by scientists at the Stanford University School of Medicine.The scientists identified a previously unsuspected job performed by the enzyme, ALDH1a1, in mice. The discovery could help guide the development of medications that extinguish the urge to consume alcohol, said Jun Ding, PhD, assistant professor of neurosurgery.Ding is the senior author of the study, published Oct. 2 in Science. The study’s lead...

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Medical Disorders of Alcoholism NEJM

Seminars in Medicine of the Beth Israel Hospital, BostonJeffrey S. Flier, M.D., Editor, Lisa H. Underhill, Assistant EditorMedical Disorders of AlcoholismN Engl J Med 1995, 333:1058-1065 October 19, 1995 DOI: 10.1056/NEJM199510193331607Systemic Effects of AlcoholInteraction between Ethanol and Other ChemicalsLong-term consumption of ethanol induces the microsomal ethanol-oxidizing system. 14 Liver-biopsy specimens from subjects who have recently drunk alcohol have a 5- to 10-fold increase in levels of cytochrome P-4502E1, the key enzyme in the oxidation of ethanol, 15 and an increase in the corresponding messenger RNA (mRNA). 16 The induction of this oxidizing system contributes to the...

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Publications, National Institute on Alcohol Abuse and Alcoholism, Harmful Interactions

Harmful Interactions Mixing Alcohol With MedicinesYou...

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Using Medicine to Treat Alcoholism: Where We Are, Where We’re Going, Addiction Recovery

A growing list of pharmacological options gives addiction recovery a boostFor as long as people have been drinking alcohol, there have attempts to use medicines to help them stop. Today, physicians who specialize in addiction treatment (American Society of Addiction Medicine, American Association of Addiction Psychiatry) use a variety of pharmacological approaches to help patients control their alcohol use, and the list of possibilities is growing rapidly. When used along with social support and psychological and behavioral interventions, medication can sometimes make the difference in reclaiming one’s life.If you’re curious about what medicine might do for you or someone you love, here’s a...

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Medicine vs. Alcoholism., Infactorium

Michael Phelps recently made news by saying he doesn...

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Beta-Carbolines Could Reduce Alcoholics’ Impulse to Drink, Medicine,

A new animal study is offering hope that a class of compounds called beta-carbolines could treat alcoholism without many of the unwanted side effects caused by current therapies.“Alcoholism is a major problem in the United States. Alcohol abuse costs almost $220 billion to the U.S. economy every year. That’s a shocking number. We need a better treatment right now,” said study lead author Phani Babu Tiruveedhula from the University of Wisconsin, Milwaukee.The exact causes of alcoholism are not well understood, but scientists explain that the urge to drink is related to the brain’s pleasure centers. They have found that alcohol triggers the brain to release dopamine, the same neurochemical...

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AA, Alcoholism and Medical Science, AA Agnostica

AA never really opened up a channel for two way communication with the medical community.My name is Brent and I’m an alcoholic, crack addict and opioid addict. So, in a nutshell, nobody special. But in qualifying as an alcoholic and addict (one in the same in my experience) I have done a lot of homework on the subject in a desperate effort to stop relapsing.Almost 6 years clean and sober as I write this in April of 2016, I was, and I stress “was”, one of those unfortunates who felt worse the longer he stayed sober. Worse in what ways? Damned if I knew but what I did know was, in 30 years of going in and out of AA, somewhere in and among the five one year medallions and two fivers, there was...

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Can you treat alcoholism with pills? - The Portland Phoenix

In an office in Portland, one of the top cities in the world for beer drinkers, Dr. Mark Publicker meets his last patient of the day, let...

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Information about Alcohol Abuse, advice for Parents, Drinking and driving consequences

Alcohol InfoNow that it has been established that alcoholism is a genetic disease of the brain, medications are being developed to assist in treatment and recovery in drug rehab programs. Drugs, medications, medicines, herbs and supplements, and nutraceuticals are all words used to describe substances that people take, maybe to cure an illness, make themselves feel better, or to diagnose a potential problem. All of these substances have an impact on the body and may potentially interact with each other. For your own safety, you need to always tell your doctor of the drugs you are taking, even if they are illegal, so that the doctor can assess your safety. We hope you find the following...

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New Medication for Alcoholism Might Already Exist

New Medication for Alcoholism Might Already ExistResearchers have suggested that an inexpensive medicine for blood pressure and angina might be an effective medication for alcoholism.The drug, pindolol, has proven effective in preclinical trials with rats. The results may or may not apply to humans. It’s clearly too early to break out the Champagne. Many promising leads in treating alcoholism have failed to materialize.Pindolol is already approved for use by the U.S. Food and Drug Administration (FDA) to treat blood pressure and angina. That approval should speed its approval for use in human clinical trials. Some doctors might also choose to use it “off-label” as a medication for...

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